Project info

  • Building
  • €3Million (Mechanical, Electrical, Process Engineering)

  • - Complete

  • 3 Months

  • 9 Months

Project info

  • Building
  • €3Million (Mechanical, Electrical, Process Engineering)

  • – Complete
  • 3 Months

  • 9 Months

Systems

  • TCU and Heat Transfer Fluid system
  • Compressed Air
  • Process Air
  • Oxygen
  • Carbon Dioxide
  • Vacuum
  • Water for Injection
  • Purified Water
  • Grade D/C HVAC Systems
  • Plant Steam & Condensate
  • CHW
  • LPHW
  • Air Conditioning
  • Natural Gas Installation
  • LV Distribution
  • Containment & Wireways
  • Stand-By Power & UPS
  • General Services & Small Power (Gen, UPS, Essential)
  • Lighting (General & Emergency)
  • Fire Detection
  • BMS & QBMS
  • Data Communication
  • Gas Detection & O2 Depletion
  • Fume Extraction Systems

Pharmaceutical Plant—Tullamore Offaly

This is the second phase of the  bioreactor scale-up project for the Zoetis facility in Tullamore. The facility previously operated a single USP train that culminates in a 500L production bioreactor.

Project Consisted of Procurement of a 1,000L Single-Use Bioreactor (SUB):This SUB will operate in conjunction with the existing 500L SUB to form a second USP train –the 500L and 1,000L production bioreactors will operate in staggered operation.

The project involved upgrades to the existing cleanroom manufacturing area within the
existing Zoetis manufacturing facility, Tullamore, Co Offaly, Ireland. The modifications to
the cleanroom involved merging some upstream and downstream processing rooms within the existing Grade D cleanroom to form larger more user friendly and adaptable processing areas which shall be based on the ”Ballroom” concept. The scale up also involved
the design and installation of a WFI generation. The project also involved replacement of
end of life utility generation systems (Chillers, Plant Steam Boilers) and replacement of Oil
with Natural Gas as the main energy source.

A new Compressed air system was designed to meet Class 1,2,1 with a full N+1 redundancy. Modification of site BMS and QBMS system was carried out.

 

Pharmaceutical Plant—Tullamore Offaly
Project Value – €500K (Mechanical, Electrical, Process Engineering)
Project Time Line – Ongoing
Design Phase: 2 Months
Construction Phase : 3 Months—Shutdown Dec 21
This Phase involves the Expansion of existing Bioreactor Room, construction of new Buffer
Store room, Analytical Lab and Retains room. OSENG were engaged to complete full M&E
design for this expansion.